Instrumentation


Instrumentation in Umeå

Bruker 850 MHz Avance III HD  - used for biomolecular solution and solid-state NMR, and 2H isotopomer experiments.
Available soon: High-field liquid-state and solid-state metabolomics
Accessories:
- 5mm TXI cryoprobe with z-gradients
- 5mm DUX-probe for deuterium experiments
- 2.5 mm (X,1H) double resonance MAS probe, 35 kHz max spin-rate
- 3.2 mm triple-resonance HCN MAS probe, 24 kHz max spin-rate
- SampleXpress sample changer
- available soon:  4 mm (1H,31P) HR-MAS probe, 15 kHz max spin-rate

850 
Bruker 600 MHz Avance III  - used for biomolecular NMR, high-throughput liquid-state metabolomics, fragment-based screening, small-molecule NMR
Accessories:
-
5mm HCN cryoprobe
- 5 mm TCI (1H, 13C, 31P) cryoprobe
-
 available soon: 5 mm BBFO cryo probe
- 5mm TXI, QXI and TBI warm probes with x,y,z-gradients
- 5mm BBO probe
-
Equipped with a SampleJet sample changer


Bruker 500 MHz Avance III – used mainly for solid-state NMR (health-, plant-, environmental sciences), non-invasive tissue metabolomics
Accessories:
- 2.5 mm triple resonance (X,Y,1H) MAS probe
- 4 mm (X,1H) MAS probe
- 4 mm (1H,13C) HR-MAS with gradient
- cooled sample changer for 4-mm MAS samples
- 7 mm (X,1H) MAS probe
- 5 mm Static double resonance (1H/X) wideline probe
- 5 mm TBI probe with z-gradients
- 5 mm H, 13C dual probe optimized for 13C detection
- 10mm BBO probe

Bruker 400 MHz Avance III – small-molecule analysis, courses, 19F-NMR and quantitative 13C-measurements
Accessories:
- 5 mm Smartprobe for X and 1H detection
- 5mm TXO probe with 19F double-resonance capabilities
- 5mm TBI probe with x,y,z-gradients
- Equipped with a BACS sample changer

 
Bruker 360 MHz DRX – used for routine NMR, courses and protein-ligand screening
Accessories:
- 5mm TBI probe with z-gradients
- 5mm Dual probe, optimized for 13C detection
- Equipped with an NMR case sample changer for 24 samples


 
Liquid handling
- Beckman Biomek 2000 for liquid handling in 96-well plate applications
- Bruker SamplePro liquid handling system where both sample solutions and NMR tube racks can be cooled and where samples can be dispensed directly into both regular 5mm NMR tubes as well as SampleJet-tubes. This system is excellently suited for preparation of samples for both fragment base screening and metabolomics.
 
   

Instrumentation in Gothenburg

Oxford 900 MHz Magnet with Bruker Avance HD III console - used for biomolecular applications
Accessories:
- 5mm TCI cryoprobe with z-gradients

Oxford 800 MHz Magnet with Bruker Avance HD III console- used for biomolecular NMR, metabolomics, fragment based screening and small-molecule NMR
Accessories:
- 5mm TXO cryoprobe with z-gradients. The four-channel probe (13C,1H,15N,2H) is equipped with cooled coils and pre-amps on all four channels.
- available soon: SampleJet sample changer

Oxford 800 MHz Magnet with Bruker Avance HD III console - used for biomolecular NMR, metabolomics, fragment based screening and small-molecule NMR
Accessories:
- 5mm TCI cryoprobe with z-gradients
- cooled SampleJet for 5x96 samples and 30 spinner positions
- 5mm QCI probe

Oxford 600 MHz Magnet with Agilent Unity Inova console - used for biomolecular applications
Accessories:
- 5mm TCI cryoprobe with z-gradients

 IMG 2550
Bruker 600 MHz Avance spectrometer  - used for diffusion NMR
Accessories:
- 5mm, 8mm, 10mm diffusion probes

 
Oxford 600 MHz Magnet with Agilent NMR S console - used for solid state applications
Accessories:
- 3.2mm (X,1H) double resonance CP-MAS probe

Oxford 500 MHz Magnet with Agilent Unity Inova console - used for general applications
Accessories:
- 5mm  HCN-probe

Liquid handling -  A Bruker liquid handling system is currently available, soon to be replaced with a Bruker Sample Pro liquid handling system where both sample solutions and NMR tube racks can be cooled and where samples can be dispensed directly into both regular 5mm NMR tubes as well as SampleJet-tubes. This system is excellently suited for preparation of samples for both fragment base screening and metabolomics
 

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